Like all electric/electronic devices nothing sounds the same. I mean, all caps sound different, all resistors sound different, all output transformers sound different and all valves too. It all depends mostly of production’s quality, the materials they are made of and who and when manufactory them.
All this factors will determinate the sound characteristic of each valve. Ones are more smooth and airy, other are more details and bright, etc...
And in tube amps there is another factor:
Bias.
Bias refers to the amount of voltage held on the grids of the output power tubes. This controls the amount of current the output tube(s) conduct exclusive of the signal current, or, looking at it another way, the amount of overlap where both tubes are conducting simultaneously.
The idle current in the output tube and the degree to which the output tubes overlap in conduction is what you're trying to adjust,
not how many volts go on the grids; you just have to use the grid volts to change the current and conduction angle.
Power tubes individually have slightly different DC gains, so the same bias voltage on two different tubes produces two different current levels. "Matched pairs" are two tubes selected to be close together.
Each power tube needs a certain bias current to keep it operating at the point where the amount and type of distortion under normal conditions is well controlled. Individual tubes vary widely in the grid bias that sets the correct idle bias current.
When i bought my first tube amp somebody says to me:
Welcome to the dark side....

and you know what? He's very right...